Projects (5)

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  • CRC 765/3: Nucleic Acid-Ligand Conjugates – Precision Tools for High Affinity and High Specificity Interactions in Chemistry and Biology (SP B01)

    Seitz, Oliver, Prof. Dr. rer. nat. (Organic and Bioorganic Chemistry III)

    Duration of Project: 01/2008 - 12/2019

    Financer: DFG: Sonderforschungsbereich - Beteiligungen

    The spatially defined display of ligands on nucleic acid architectures enables explorations of scope and specificity of multivalent binding. We will address fundamental questions about the reach and specificity of multivalency. Is there a distance li ...

  • PP 1623: Peptide-Templated Bioconjugation with Proteins on and in Living Cells for Investigations of GPCR Transport and Cross-Reactivity

    Seitz, Oliver, Prof. Dr. rer. nat. (Organic and Bioorganic Chemistry III)

    Duration of Project: 02/2016 - 06/2019

    Financer: DFG: Sachbeihilfe

    The functional properties of G-protein coupled receptors (GPCRs) depend on localisation, density of surface expression and their mobility in the cell membrane. Some GPCRs undergo dynamic equilibria between monomeric and dimeric forms. Microscopic ima ...

  • PP 1784: Cellular Imaging of RNA C-to-U Editing

    Seitz, Oliver, Prof. Dr. rer. nat. (Organic and Bioorganic Chemistry III)

    Duration of Project: 01/2016 - 06/2019

    Financer: DFG: Sachbeihilfe

    RNA editing impacts RNA splicing and protein translation. The recent progress in high-throughput RNA sequencing has revealed an increasing number of mRNA editing sites. However, these methods provide an overview about the editing state of an ensemble ...

  • PP 1879: Nucleotide Second Messenger Signaling in Bacteria/Coordination Fund

    Hengge, Regine, Prof. Dr. (Microbiology)

    Duration of Project: 09/2019 - 08/2022

    Financer: DFG - Schwerpunktprogramme

    The DFG priority programme SPP 1879 is a research consortium studying bacterial second messenger signalling that currently funds 18 research projects at German universities and other research institutions. By including representatives of all clades o ...

  • PP 1879: Nucleotide Second Messenger Signaling in Bacteria/Coordination Project

    Hengge, Regine, Prof. Dr. (Microbiology)

    Duration of Project: 09/2016 - 08/2020

    Financer: DFG - Schwerpunktprogramme

    The overall goal of SPP 1879 over the next six years is to built a tightly collaborating and internationally radiating scientific community in the highly dynamic field of bacterial nucleotide second messenger signalling. Achieving this goal not only ...

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