Projects (62)

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  • Targeted Salix Crossing and Chemoprofiling for Improved Medicinal Potential of Willow Bark

    Ulrichs, Christian, Prof. Dr. rer. nat.; Dr. rer. agr. (Urban Plant Ecophysiology)

    Duration of Project: 07/2017 - 02/2021

    Financer: BMBF

    Deforestation of Salix species for fuel as renewable sources for energetic use had priority in the past. However, the mobilization of dendromass from forests is limited and therefore, short-rotation plantations (SRP) with fast-growing tree species su ...

  • RTG 2473/1: Bioactive Peptides – Innovative Aspects of Synthesis and Biosynthesis

    Seitz, Oliver, Prof. Dr. rer. nat. (Organic and Bioorganic Chemistry III)

    Duration of Project: 04/2019 - 09/2023

    Financer: DFG: Graduiertenkollegs - Beteiligungen

    The Research Training Group (RTG) “Bioactive Peptides – Innovative Aspects of Synthesis and Biosynthesis” aims to provide a structured curriculum on peptide research for doctoral students. In the past years, peptide research has become of significant ...

  • RTG 2424/1: Computational Methods for Oncology: Towards Personalized Therapies in Cancer

    Leser, Ulf, Prof. Dr.-Ing. (Knowledge Management in Bioinformatics)

    Duration of Project: 06/2019 - 11/2023

    Financer: DFG: Graduiertenkollegs - Beteiligungen

    Recent advances in DNA sequencing and molecular profiling have triggered a major shift in cancer research. Traditional coarse-grained and phenomenological examinations and therapy decisions are replaced by individualized approaches that integrate mol ...

  • RTG 2386/1: Extrospection. External Access to Higher Cognitive Processes.

    Pauen, Michael, Prof. Dr. (Philosophy of Spirit)

    Duration of Project: 10/2018 - 03/2023

    Financer: DFG: Graduiertenkollegs

    Higher cognitive processes like emotions, perception, belief formation or mind-reading are of essential importance in philosophy, psychology, neuroscience, and psychiatry. It is quite controversial, though, to what extent these processes and particul ...

  • RTG 2046/2: “Parasite Infections: From Experimental Models to Natural Systems” (TP C8)

    Heitlinger, Emanuel, Prof. Dr. rer. nat. (Ecology and Evolution molecularly Parasite-Host-Interactions)

    Duration of Project: 10/2019 - 03/2024

    Financer: DFG: Graduiertenkollegs

    There is a growing gap in training opportunities in modern parasitology in Germany and beyond. This bottleneck is in clear contrast to the worldwide distribution of parasitic diseases in human and animal populations, with a steady increase due to dru ...

  • RTG 2046/2: “Parasite Infections: From Experimental Models to Natural Systems” (SP B1)

    Matuschewski, Kai, Prof. Dr. (Molecular Parasitology II)

    Duration of Project: 10/2019 - 03/2024

    Financer: DFG: Graduiertenkollegs

    There is a growing gap in training opportunities in modern parasitology in Germany and beyond. This bottleneck is in clear contrast to the worldwide distribution of parasitic diseases in human and animal populations, with a steady increase due to dru ...

  • RTG 2046/2: “Parasite Infections: From Experimental Models to Natural Systems” (SP A2)

    Gupta, Nishith, Dr. (Molecular Parasitology II)

    Duration of Project: 10/2019 - 06/2021

    Financer: DFG: Graduiertenkollegs

    There is a growing gap in training opportunities in modern parasitology in Germany and beyond. This bottleneck is in clear contrast to the worldwide distribution of parasitic diseases in human and animal populations, with a steady increase due to dru ...

  • RTG 2046/2: “Parasite Infections: From Experimental Models to Natural Systems”

    Matuschewski, Kai, Prof. Dr. (Molecular Parasitology II)

    Duration of Project: 10/2019 - 03/2024

    Financer: DFG: Graduiertenkollegs

    Parasites cause serious, health-depriving, disabling diseases affecting people and animals alike. These pathogens are globally distributed, prevalent, heterogeneous and extremely complex. There is a necessity and growing demand for interdisciplinaril ...

  • Progress in phenological modelling on the basis of metabolomic approaches

    Chmielewski, Frank-M., Prof. Dr. rer. nat. habil. (Agriculture and Plant Cultivation)

    Duration of Project: 07/2014 - 12/2017

    Financer: DFG: Sachbeihilfe

    Modelling of phenological stages, such as the flowering of fruit trees, is based on temperature sums for many decades, describing both the chilling and the forcing requirements of woody plants until the beginning of flowering. These approaches go bac ...

  • PROCOPE 2020 "Brain Roads. Interactive Visualization of the Brain, involving Neurosurgery"

    Schäffner, Wolfgang, Prof. Dr. (Cluster of Excellence 'Matters of Activity')

    Duration of Project: 01/2020 - 12/2021

    Financer: DAAD
    Neurosurgical practices are progressively guided by tomographic scanning technologies with increasing
    anatomical details, such as magnetic resonance imaging (MRI). These tomographic image technologies
    enable presurgical analysis and planning, as we ...
  • Learning of Intelligent Swarm Behavior - EXC 2002 SCoI P 12

    Romanczuk, Pawel, Dr. (Junior Research Groups)

    Duration of Project: 06/2019 - 08/2022

    Financer: DFG-Exzellenzinitiative: Cluster

    The main objective of the project is to systematic quantification of collective behavior of fish in order to derive data-driven models of observed collective behavior across different ecological contexts. Here, two important ecological contexts shall ...

  • IRTG 2403/1: Main Account

    Ohler, Uwe, Prof. Dr. (Systems Biology of Gene Regulation (S))

    Duration of Project: 01/2019 - 06/2023

    Financer: DFG: Graduiertenkollegs

    The aim of the IRTG "Dissecting and Reengineering the Regulatory Genome" is to identify and characterise regulatory processes and DNA sequences that determine the activity of gene expression in eukaryotes. The researchers in Berlin, Germany, and Durh ...

  • IRTG 2403/1: Dissecting and Reengineering the Regulatory Genome

    Ohler, Uwe, Prof. Dr. (Systems Biology of Gene Regulation (S))

    Duration of Project: 01/2019 - 06/2023

    Financer: DFG: Graduiertenkollegs

    The aim of the IRTG “Dissecting and Reengineering the Regulatory Genome” is to identify and characterise regulatory processes and DNA sequences that determine the activity of gene expression in eukaryotes. The researchers in Berlin, Germany, and Durh ...

  • IRTG 2290/1: Crossing Boundaries: Molecular Interactions in Malaria

    Matuschewski, Kai, Prof. Dr. (Molecular Parasitology)

    Duration of Project: 09/2017 - 02/2022

    Financer: DFG: Graduiertenkollegs

    Malaria is caused by single-celled parasites known as Plasmodium, which are transmitted by the bite of the Anopheles mosquito. Some basic principles of the progress of the disease and parasite-host interactions are still not understood. The German-Au ...

  • Intrasurgical stimulation of the human cerebral cortex – from basic physiology to cognition

    Brecht, Michael, Prof. Dr. (Animal Physiology/Systems Neurobiology and Neural Computation)

    Duration of Project: 11/2017 - 12/2018

    Financer: DFG-Exzellenzinitiative: Cluster

    Under the supervision of Peter Vajkoczy the cortices of a large number of awake neurosurgical patients are surface stimulated in order to spare movement/speech relevant cortical tissues during surgical intervention. So far, the implications of such s ...

  • International Conference "Genom Editing with CRISPR", September 2019 in Berlin

    Ehrenhofer-Murray, Ann, Prof. Dr. (Molecular Cell Biology)

    Duration of Project: 07/2019 - 09/2019

    Financer: Sonstige Stiftungen

    The discovery of the clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins in bacteria and archaea and the successful application of such CRISPR-Cas systems as a tool for genome editing have revoluti ...

  • Integrated Climate Change Impact Assessment of the Coffee Sector Using a Combination of Agro-Ecological Niche Modeling and a Partial Equilibrium Model of the Agricultural Sector

    Kirschke, Dieter, Prof. Dr. Dr. h. c. (Agricultural Politics)

    Duration of Project: 09/2011 - 08/2014

    Biophysical impact models project a highly negative direct impact of climate change on the coffee crop. As plantations have a lifespan of several decades pro-active adaptive actions must be taken now. Climate change impact assessments that intend to ...

  • Institutional Implications of the Expansion of the Bioeconomy

    Bokelmann, Wolfgang, Prof. Dr. rer. nat. habil. (Economics of Horticultural Production)

    Duration of Project: 02/2017 - 07/2019

    Financer: BMBF

    The project identifies institutional arrangements and legal regulations which contribute to achieving public acceptance of the expansion of land use based bioeconomy. It explores innovative institutional arrangements which ensure agricultural structu ...

  • Insight: Neuroscientific Investigations of Knowledge Effects on Visual Perception and Awareness

    Abdel Rahman, Rasha, Prof. Dr. rer. nat. (Neuralcognitive Psychology)

    Duration of Project: 10/2017 - 12/2020

    Financer: DFG: Sachbeihilfe

    According to classic and current models visual perception can be viewed as encapsulated in the sense that it is not modulated by cognitive factors such as expectations or prior knowledge. Yet, evidence is cumulating that even verbally transmitted kno ...

  • Identification of New Candidate Genes for Insulin Sensitivity and Insulin Resistance in the Berlin Fat Mouse

    Hesse-Wilting, Deike, Dr. (Breeding Biology and Molecular Animal Breeding)

    Duration of Project: 09/2018 - 08/2021

    Financer: DFG: Eigene Stelle (Sachbeihilfe)

    Insulin resistance is the reduced responsiveness of cells and tissues to insulin and can ultimately proceed to type 2 diabetes. The aim of the proposed project is to further clarify the genetic causes for insulin resistance as well as the maintenance ...

  • Identification and Analysis of Genes Involved in Tetrapyrrole Metabolism and Plastid-Derived ROS-Mediated Signaling in Chlamydomonas Reinhardtii

    Grimm, Bernhard, Prof. Dr. rer. nat. Prof. Dr. (Plant Physiology)

    Duration of Project: 07/2019 - 07/2021

    Financer: DFG: Sachbeihilfe

    The tetrapyrrole biosynthesis (TBS) is tightly controlled at the transcriptional and the posttranslational level. Due to photooxidative stress caused by accumulating tetrapyrrole intermediates, multiple factors are required for a fine-tuned metabolic ...

  • Genomic Characterization and Evolutionary Dynamics of Developmental Gene Regulatory Networks of Paracentrotus lividus (Echinodermata: Echinoidea)

    Garfield, David, Dr. (Junior Research Groups)

    Duration of Project: 10/2019 - 09/2020

    Financer: DAAD
    Mutations impacting DNA regulatory elements make a disproportionate contribution to evolutionary processes and are important contributors to inter-individual variation in disease susceptibility.
    We are, however, limited in our ability to predict *w ...
  • Genetic basis of the hornwort’s carbon-concentrating mechanism

    Wicke, Susann, Prof. Dr. (Systematik Botany and Biodiversity)

    Duration of Project: 09/2020 - 08/2023

    Financer: DFG - Schwerpunktprogramme

    Biophysical carbon concentrating mechanisms (CCMs) operating at the single-cell level have evolved independently in some eukaryotic algae and a single lineage of land plants, the hornworts. An essential component for an efficient biophysical CCM is a ...

  • Function and Stimulation of the Transient Increase of the Leaf Apoplastic pH During Exposure to Chlorine-Stress

    Geilfus, Christoph-Martin, Prof. Dr. (Controlled Environment Horticulture)

    Duration of Project: 07/2018 - 07/2021

    Financer: DFG: Sachbeihilfe

    The apoplast is an extracellular compartment that lies outside the plasma membrane (PM). External stress factors can influence the pH of the fluid film of the leaf apoplast. For instance, the apoplastic pH (pHapo) of field bean (Vicia faba L.) leaves ...

  • Functional in vivo Studies of Algal Sensory Photoreceptors

    Hegemann, Peter, Prof. Dr. (Experimental Biophysics)

    Duration of Project: 06/2019 - 05/2021

    Financer: DFG: Sachbeihilfe

    Channelrhodopsins, that we originally discovered in the green alga Chlamydomonas reinhardtii and described as a light-gated ion channels, revolutionized the field of neuroscience over the past decade by enabling neuroscientists to specifically activa ...

  • Functional and Physiological Significance of Phosphatidylethanolamine Synthesis in the Protozoan Parasite Toxoplasma Gondii

    Gupta, Nishith, Dr. (Molecular Parasitology II)

    Duration of Project: 06/2019 - 09/2019

    Financer: DFG: Sonstiges
  • FOR 2569/2: Efficiency of agricultural land markets – The role of liquidity and competition

    Odening, Martin, Prof. Dr. agr. habil. (Agricultural Farm Management)

    Duration of Project: 08/2020 - 07/2023

    Financer: DFG: Forschergruppen
    Subproject 2 investigates price formation on agricultural land markets
    considering the interplay of (incomplete) competition, structural
    change, and market liquidity. The core question is: Are observed land
    transactions and prices the outcome of a ...
  • FOR 2569/2: Efficiency of agricultural land markets – The role of liquidity and competition

    Ritter, Matthias, Prof. Dr. (Quantitative Agricultural Economics especially Applied Econometrics)

    Duration of Project: 08/2020 - 07/2023

    Financer: DFG: Forschergruppen

    Subproject 2 investigates price formation on agricultural land markets considering the interplay of (incomplete) competition, structural change, and market liquidity. The core question is: Are observed land transactions and prices the outcome of an e ...

  • FOR 2569/1: Market integration and border effects in agricultural land markets (SP 02)

    Ritter, Matthias, Prof. Dr. (Quantitative Agricultural Economics especially Applied Econometrics)

    Duration of Project: 08/2017 - 04/2022

    Financer: DFG: Forschergruppen

    This subproject contributes to the overall objective of the research unit by empirically studying spatial price diffusion of agricultural land markets. We borrow the notion of spatial market integration from commodity price analysis and question whet ...

  • FOR 2569/1: Market integration and border effects in agricultural land markets (SP 02)

    Odening, Martin, Prof. Dr. agr. habil. (Agricultural Farm Management)

    Duration of Project: 08/2017 - 04/2022

    Financer: DFG: Forschergruppen

    This subproject contributes to the overall objective of the research unit by empirically studying spatial price diffusion of agricultural land markets. We borrow the notion of spatial market integration from commodity price analysis and question whet ...

  • FOR 2569/1: Agricultural Land Markets - Efficiency and Regulation (SP 07)

    Lakes, Tobia, Prof. Dr. (Applied GIScience)

    Duration of Project: 10/2017 - 01/2021

    Financer: DFG: Forschergruppen

    Agricultural land markets in Germany have changed substantially in the last decade, with rapidly increasing land sales and land rental prices. As a result, the spatial configuration of agricultural land use has changed, with a trend towards a higher ...

  • FOR 2092/2: Auxiliary Factors for Chlorophyll Biosynthesis and Their Potential Contribution to the Assembly of Chlorophyll Into Chlorophyll-Binding Proteins (SP 03)

    Grimm, Bernhard, Prof. Dr. rer. nat. Prof. Dr. (Plant Physiology)

    Duration of Project: 11/2017 - 01/2021

    Financer: DFG: Forschergruppen

    Chlorophyll biosynthesis provides the essential pigments for photosynthesis in photoautotrophic organisms. While almost all enzymatic steps of have been elucidated, the spatio-temporal organization of the pathway as well as its functional coupling to ...

  • Field Potentials in the Auditory System

    Kempter, Richard, Prof. Dr. (Computational Neuroscience)

    Duration of Project: 04/2016 - 06/2020

    Financer: BMBF

    Feldpotentiale können nicht-invasiv auf der Oberfläche des Kopfes gemessen werden. Sie können zum Beispiel durch akustische Stimuli erzeugt werden. Dieses Auditorische Hirnstammpotential hat erhebliche klinische Relevanz, aber trotzdem ist unklar, wi ...

  • EXIST-Founding Scholarship

    Upmeier zu Belzen, Annette, Prof. Dr. (Biology Education)

    Duration of Project: 01/2017 - 12/2017

    Financer: Bundesministerium für Wirtschaft und Technologie

    App-basierte und problemorientierte Lernumgebung für das personalisierte Erwerben von Fachwissen im MINT-Bereich und von Kompetenzen der Erkenntnisgewinnung. // Das Ziel der Ausgründung ist das Angebot einer personalisierten problembasierten Lernumge ...

  • Establishment of Global Histone Acetylation Patterns by HAT Complex SAS-I in S. cerevisiae

    Ehrenhofer-Murray, Ann, Prof. Dr. (Molecular Cell Biology)

    Duration of Project: 08/2013 - 07/2014

    Financer: DFG: Sachbeihilfe

    Eukaryotic organisms require sophisticated mechanisms to ensure that gene expression in their genome is carried out in the correct temporal and spatial manner. Posttranslational histone modifications are one mechanism by which gene expression is cont ...

  • ENCODS 2018, Science & Society Session “Methods of an Embodied Mind”

    Brecht, Michael, Prof. Dr. (Animal Physiology/Systems Neurobiology and Neural Computation)

    Duration of Project: 03/2018 - 09/2018

    Financer: Sonstige Stiftungen

    The project is part of the students’ conference ENCODS 2018 (Satellite of the FENS Froum 2018 in Berlin). Participants are encouraged to discover how their research impacts society.

  • Zouni, Athina, PD Dr. (Honorary Chairs / Professors by Special Appointment / Part-Time Lecturers)

    Duration of Project: 01/2019 - 12/2022

    Financer: DFG-Exzellenzinitiative: Cluster

    Oxygen photosynthesis in green plants, algae and cyanobacteria is catalyzed by two large membrane protein complexes Photosystem I (PSI) and Photosystem II (PSII). Both complexes contain a reaction center (RC) that conducts a light-driven charge trans ...

  • Development of a System for Quality Assurance and Refinement of Animal Experiments With Sheeps Based on Objective Sensory Behaviour Parameters

    Schmidt, Uwe, Prof. Dr. (Section Biological Systems Technology)

    Duration of Project: 11/2019 - 10/2022

    Financer: Bundesministerium für Wirtschaft und Technologie

    The distress of the animals in current animal experiments is often determined by screening and scoring of health and experimental relevant symptoms, which is carried out by veterinarians and animal caretakers by means of mostly paper-based anaesthesi ...

  • Development of a SNP Chip for Breeding Value Estimation and Management of Genetic Diversity in German Black Pied Cattle

    Brockmann, Gudrun A., Prof. Dr. rer. nat. habil. (Breeding Biology and Molecular Animal Breeding)

    Duration of Project: 04/2019 - 07/2022

    Financer: Bundesanstalt für Landwirtschaft und Ernährung

    The project aims at the development and testing of a custom-made SNP chip that is specific for the cattle breed DSN and that is suited for the genomic breeding value estimation and the management of the genomic diversity in the small breed. The proje ...

  • Development of an Integrated Fertilization and Irrigation Management for Protected Cultivation of Horticultural Crops Using Non-Invasive Sensors

    Schmidt, Uwe, Prof. Dr. (Section Biological Systems Technology)

    Duration of Project: 08/2016 - 12/2017

    Financer: Bundesanstalt für Landwirtschaft und Ernährung

    Within the scope of future cooperation, the fertilization and irrigation management for protected cultivation of vegetable crops in China should be optimized with the use of non-invasive sensor technologies. There, the long-time experience of the Dep ...

  • Development of a Module-Based Crop Protection Strategy, Taking Into Account Sustainable and Environmentally Friendly Methods to Control Sea Buckthorn Fruit Fly

    Schmidt, Uwe, Prof. Dr. (Section Biological Systems Technology)

    Duration of Project: 08/2018 - 10/2022

    Financer: Brandenburg/ Sonstige
    In federal land Brandenburg, cultivation of sea buckthorn Hippophae rhamnoides L is threatened by the fruit fly Rhagoletis batava HER. Fruit damage can be up to 80 %. Farmers are in dire need of a reliable control strategy.
    Project MoPlaSa is develo ...
  • Design and Management of Integrative Innovation Processes: New Institutional and Regional Coordination Forms for Sustainable Land Management

    König, Bettina, Dr. (Economics of Horticultural Production)

    Duration of Project: 09/2014 - 12/2019

    Financer: BMBF

    The aim of ginkoo is the transdiciplinary development of an innovation management model for managing complex innovations processes for sustainable land management solutions by coordinating actors. The model consists of single tools for ex-ante sustai ...

  • Deciphering the principles of cell decision-making in multicellular systems: The Least microEnvironmental Uncertainty Principle (LEUP)

    Erhardt, Marc, Prof. Dr. (Bacterial Physiology)

    Duration of Project: 01/2020 - 12/2024

    Financer: Volkswagen-Stiftung (VW)

    Cell decision-making is the process of cells changing their phenotype according to their intrinsic programming and in response to the microenvironmental cues. Currently, little is known about the principles dictating cell decision-making in multicell ...

  • Deciphering the First Complete Mitochondrial Genomes From Appendicularia (Chordata: Tunicate)

    Stach, Thomas, PD Dr. (Molecular Parasitology II)

    Duration of Project: 01/2019 - 12/2021

    Financer: German Israel Foundation

    The phylogenetic position of Appendicularia might be crucial for the understanding of the evolution of early vertebrates. The aim of our project is to sequence complete mitochondrial genomes in order to substantiate hypotheses concerning the phylogen ...

  • Cyclic di-AMP metabolism and functions in Streptomyces

    Tschowri, Natalia, Dr. rer. nat. (Junior Research Groups)

    Duration of Project: 03/2020 - 03/2023

    Financer: DFG - Schwerpunktprogramme

    The bacterial second messenger bis-(3’,5’)-cyclic dimeric adenosine monophosphate (c-di-AMP) is produced by diadenylate cyclases with a conserved DAC domain and degraded by DHH-DHHA1 or HD domain-containing phosphodiesterases (PDEs). In bacteria, it ...

  • Cluster of Excellence 2049: NeuroCure

    SZF-1, Leitung Servicezentrum Forschung, (Research Service Centre)

    Duration of Project: 01/2019 - 12/2025

    Financer: DFG Exzellenzstrategie: Cluster

    Neurological and psychiatric disorders pose a massive burden to society, and our understanding of the underlying molecular and pathophysiological mechanisms is limited. In addition, translation of knowledge into clinical advances has proven difficult ...

  • Cluster of Excellence 2008: UniSysCat

    SZF-1, Leitung Servicezentrum Forschung, (Research Service Centre)

    Duration of Project: 01/2019 - 12/2025

    Financer: DFG Exzellenzstrategie: Cluster

    The central scientific objective of UniSysCat (Unifying Systems in Catalysis) is to master the next stage of future challenges in catalysis: how to elucidate, create, and control reaction networks in chemical and biological catalysis at different lev ...

  • A Quantitative Force Map of the Mitotic Spindle

    Reber, Simone, (Integrative Research Institute for the Life Sciences (IRILS))

    Duration of Project: 05/2018 - 07/2021

    Financer: DFG: Sachbeihilfe

    The goal of this research proposal is to understand the way in which cells engineer micrometerscale structures. In particular, we aim to understand how different force generating systems collectively define the shape of the metaphase spindle. The bip ...

  • A Novel Lipid (Phosphatidylthreonine)-Regulated Calcium Homeostasis in Toxoplasma Gondii

    Gupta, Nishith, Dr. (Molecular Parasitology II)

    Duration of Project: 02/2019 - 01/2022

    Financer: DFG: Sachbeihilfe
    The major membrane glycerophospholipid classes, described thus far, include phosphatidylcholine,
    phosphatidylethanolamine, phosphatidylserine (PtdSer) and phosphatidylinositol. Our recent work has
    demonstrated the natural occurrence and genetic ori ...
  • Ehrenhofer-Murray, Ann, Prof. Dr. (Molecular Cell Biology)

    Duration of Project: 09/2019 - 09/2019

    Financer: DFG: Sonstiges

    The discovery of the clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins in bacteria and archaea and the successful application of such CRISPR-Cas systems as a tool for genome editing have revoluti ...

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