Projects (26)

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  • Quality Management in Assembly of Bacterial Type III Secretion Systems – A Comparative Analysis of the Construction of Flagella and Injectisomes

    Erhardt, Marc, Prof. Dr. (Bacterial Physiology)

    Duration of Project: 10/2019 - 09/2022

    Financer: DFG: Sachbeihilfe

    Protein export via type III secretion systems (T3SS) is essential for the self-assembly of bacterial flagella as well as for construction and function of virulence-associated injectisomes of many Gram-negative pathogens, including Salmonella enterica ...

  • Quantifying Liver Perfusion-Function Relationship in Complex Resection - A Systems Medicine Approach (QuaLiPerF)

    König, Matthias, Dr. (Junior Research Groups)

    Duration of Project: 03/2021 - 02/2025

    Financer: DFG: Eigene Stelle (Sachbeihilfe)

    Complex, extended liver resections (ePHx) pose a high risk of postoperative liver failure, especially in case of preexisting liver disease. We aim to improve our mechanistic understanding of the interplay between hepatic perfusion and function to an ...

  • Reconstructing the Evolution of Transcription Factor DNA Binding Specificity Across Living Species and Their Common Ancestors

    Muino Acuna, Jose Maria, Dr. Ph.D. (Systems Biology of Gene Regulation (S))

    Duration of Project: 11/2018 - 11/2021

    Financer: DFG: Eigene Stelle (Sachbeihilfe)

    Transcription factors (TFs) are major regulators of developmental processes and environmental adaptation in plants and animals. They achieve their function by binding to a specific set of DNA regions. However, it is not well understood how their DNA- ...

  • Regulation of kinetochore function in yeast by modification of the core region of the centromeric nucleosome

    Ehrenhofer-Murray, Ann, Prof. Dr. (Molecular Cell Biology)

    Duration of Project: 02/2020 - 01/2023

    Financer: DFG: Sachbeihilfe

    Centromeres are the regions of the chromosome where the kinetochore is assembled, and they establish a physical link between the centromeric chromatin and the microtubule for chromosome segregation in mitosis. In Saccharomyces cerevisiae, centromeric ...

  • Rural Decisions

    Kirschke, Dieter, Prof. Dr. Dr. h. c. (Agricultural Politics)

    Duration of Project: 06/2009 - 07/2012

    Financer: Europäische Union (EU)

    Current political and scientific debates are focused on finding a long-term policy beneficial both for environment and economy in rural areas in the EU member states. The research project aims to methodologically reinforce these efforts and to contri ...

  • The Economics of Biogas Production

    Kirschke, Dieter, Prof. Dr. Dr. h. c. (Agricultural Politics)

    Duration of Project: 01/2012 - 04/2014

    The project analyses the efficiency of the Renewable Energy Sources Act and accompanying costs of CO2-reduction in the field of biogas production in Germany. The study focuses on the calculations of regional CO2-mitigation potentials and CO2-mitigati ...

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