Human Brain Project – SGA2

Feedback circuits, and apical amplification.
Our goal is to examine the circuits that create cortical feedback in a temporally precise and contextual manner. Our hypothesis is that the long range input to supra-granular layer of cortex is the principal locus of feedback. We test this hypothesis in mouse models where it is possible to obtain a mechanistic understanding of the temporal, contextual and laminar activation pattern

Principal Investigators
Larkum, Matthew Prof. Dr. (Details) (Neuronal Plasticity)

participating organizational facilities of the HU

Duration of Project
Start date: 04/2018
End date: 03/2020

Last updated on 2021-04-01 at 17:47