SFB 429 II-III: Structure and function of conserved plastid open reading frames in Synechocystis sp. PCC6803

The complete sequence of plastid genomes of many plants and algae revealed a number of conserved hypothetical open reading frames (ycf) with unknown function. Most of these ORFs are found also in the sequenced genomes of cyanobacteria. For some of these putative gene products a function in the photosynthetic processes was shown. They are involved in the assembly and/or stability of the photosystems.

We are working on the open reading frames ycf3, ycf4, ycf37. Phenotypic effects in the knockout mutants and biochemical studies indicate a function of these proteins in the stability or assembly of photosystem I.

Principal Investigators
Grimm, Bernhard Prof. Dr. rer. nat. (Details) (Collaborative Research Centre 429 'Molecular Physiology, Energetics and Regulation of Primary Plant Metabolism Processes')

Duration of Project
Start date: 01/2002
End date: 12/2010


Wilde, A.; Lünser, K.; Ossenbühl, F.; Nickelsen, J.; Börner, T.: Characterization of the cyanobacterial ycf37: mutation decreases the photosystem I content. Biochem J. 2001 Jul 1;357(Pt 1):211-6.

Hübschmann, T; Wilde, A.; Elanskaya, I.; Shestakov, S.V.; Börner, T.: A putative cytochrome c biogenesis gene in Synechocystis sp. PCC 6803. FEBS Lett. 1997 May 19;408(2):201-5.

Wilde, A.; Härtel, H.; Hübschmann, T.; Hoffmann, P.; Shestakov, S.V.; Börner T.: Inactivation of a Synechocystis sp strain PCC 6803 gene with homology to conserved chloroplast open reading frame 184 increases the photosystem II-to-photosystem I ratio. Plant Cell. 1995 May;7(5):649-58.

Last updated on 2020-10-03 at 16:30