Synthesis and modification of biopolymers


Principal investigators
Seitz, Oliver Prof. Dr. rer. nat. (Details) (Organic and Bioorganic Chemistry III)

Financer
Schering AG

Duration of project
Start date: 08/2003
End date: 07/2008

Publications

"Activating protecting groups for the solid phase synthesis and modification of peptides, oligonucleotides and oligosaccharides" O. Seitz in Organic Synthesis Highlights V (H.G. Schmalz, T. Wirth; Eds.) 2003, 230-250, Wiley-VCH, Weinheim.



"The chemical total synthesis of proteins" O. Seitz in Organic Synthesis Highlights V (H.G. Schmalz, T. Wirth; Eds.) 2003, 368-383, Wiley-VCH, Weinheim.



"Synthesis of protein-nucleic acid conjugates by expressed protein ligation" M. Lovrinovic, R. Wacker, H. Schroeder, O. Seitz, R. Seidel, M. Engelhard, R. Goody and C. M. Niemeyer, Chem. Commun. 2003, 822-823.



"Glycopeptides and Glycoproteins: Synthetic Chemistry and Biology" O. Seitz, Carbohydrate Based Drug Discovery (C.-H. Wong; Ed.), 2003, Wiley-VCH, Weinheim, 169-214.



"Glycopeptides and Glycoproteins: Synthetic Chemistry and Biology" O. Seitz, Chemical Probes in Biology (Schneider; Ed.), 2003, Kluwer, 21-33.



"DNA Synthesis and DNA Hybridization" S. Ficht, W. Hecker, A. Mattes, O. Seitz, Chemical Biology A Practical Course (H. Waldmann, P. Janning; Eds.), 2004, Wiley-VCH, Weinheim, 23-34.



"Doubly-labeled Pepti"Homogenous DNA Detection" O. Seitz, Chemical Probes in Biology (Schneider; Ed.), 2003, Kluwer, 287-296.



"Thiazole orange as fluorescent universal base in PNA" O. Köhler, O. Seitz*, Chem. Commun. 2003, 2938-2939.



"Homogenous DNA Detection" O. Seitz, Bioorganic Chemistry Highlights II (C. Schmuck, H. Wennemers; Eds.), 2004, Wiley-VCH, Weinheim, 311-328.



"Ensemble hybridisation - A new method for exploring sequence dependent fluorescence of dye-nucleic acid conjugates " O. Köhler, D. V. Jarikote, O. Seitz*, Chem. Commun. 2004, 2674-2675.



"Forced Intercalation Probes (FIT-Probes) ­ Thiazole Orange as a Fluorescent Base in Peptide Nucleic Acids for Homogeneous SNP Detection" (Cover) O. Köhler, D. V. Jarikote, O. Seitz*, ChemBioChem. 2005, 6, 69-77.



"Forced Intercalation as Tool in Gene Diagnostics and in Studying DNA-Protein Interactions" O. Köhler, D. V. Jarikote, I. Singh, V.S. Parmar, E. Weinhold, O. Seitz*, Pure & Appl. Chem. 2005, 77, 327-338.



"Linear and Divergent Solid-Phase Synthesis of Peptide Nucleic Acids Containing Thiazole Orange as Artificial Base" (Cover) D. V. Jarikote, O. Köhler, E. Socher, O. Seitz*, Eur. J. Org. Chem. 2005, 3187 - 3195.



de Nucleic Acids (PNAs) as Probes for the Detection of DNA Point Mutations"
O. Köhler, S. Röttger, O. Seitz, Chemical Biology A Practical Course (H. Waldmann, P. Janning; Eds.), 2004, Wiley-VCH, Weinheim, 35-44.



"Synthesis of 6-O-benzylguanine and its conjugation with linkers" C. Barth, O. Seitz, H. Kunz, Zeitschr. Naturf. 2004, 59, 802-806.



"Direct Carbodiimide-Mediated Conjugation of Carboxylates Using Pyridinium p-Toluenesulfonate and Tertiary Amines as Additives " S. Ficht, L. Röglin, M. Ziehe, D. Breyer, O. Seitz*, Synlett 2004, 2525-2528.


Last updated on 2022-08-09 at 01:07