Experimental study on optimising of the sensitive liquid for measuring spezific changes of the colloid-osmotic pressure and of the viscosity in dependence on the glucose concentration.


The project comprises laboratory investigations with new micromechanic devices and microdialysis membranes for optimising long-term stability of the sensitive liquid, consisting of ConA and different polymer glycoligands. The project is focusing on optimising and stabilising characteristic curves for the glucose-dependent colloid-osmotic pressure and viscosity.
Key missions of the project are elaboration of biochemical basis for the colloid-osmotic measuring principle using different dextran dispersities, development and proving of inclusion principles for the senstive liquids in very small microdialysis chambers taking in account of the system requirements of the micromechanics, the proving of viscosimetric glucose sensors, and the analysis of physiologically relevant milieu factors.

Principal Investigators
Ehwald, Rudolf Prof. i. R. Dr. rer. nat. (Details) (Cell Biology)

Duration of Project
Start date: 12/2009
End date: 08/2011

Last updated on 2020-13-03 at 23:07