Spatio-temporal dynamics of calcium release


As an important example of spatial and stochastic effects in cell signalling, we study the role of fluctuations during the nucleation and propagation of waves of cytosolic calcium. Briefly, calcium is an important second messenger in cellular communications. The liberation and uptake by cellular stores such as the endoplasmic reticulum (ER) and reactions with buffer proteins determine its intracellular dynamics.
As an important example of spatial and stochastic effects in cell signalling, we study the role of fluctuations during the nucleation and propagation of waves of cytosolic calcium. Briefly, calcium is an important second messenger in cellular communications. The liberation and uptake by cellular stores such as the endoplasmic reticulum (ER) and reactions with buffer proteins determine its intracellular dynamics.


Principal investigators
Rüdiger, Sten Dr. (Details) (Theoretical Physics / Statistical Physics and Nonlinear Dynamics)

Duration of project
Start date: 10/2011
End date: 07/2015

Last updated on 2020-10-12 at 15:15