Inhibition of micro RNA maturation by small molecules

Micro RNAs (miRNAs) are small regulatory RNA molecules. MiRNAs are synthesiszed as inactive hairpin-shaped precursor molecules. The latter are cleaved by a ribonuclease called Dicer to form the active miRNAs. Our goal is to inhibit this miRNA maturation step by small molecules.

Principal Investigators
Arenz, Christoph Prof. Dr. (Details) (Organic Synthesis)

DFG: Sachbeihilfe

Duration of Project
Start date: 03/2007
End date: 02/2010

Last updated on 2020-09-03 at 23:21