Inhibition of micro RNA maturation by small molecules

Micro RNAs (miRNAs) are small regulatory RNA molecules. MiRNAs are synthesiszed as inactive hairpin-shaped precursor molecules. The latter are cleaved by a ribonuclease called Dicer to form the active miRNAs. Our goal is to inhibit this miRNA maturation step by small molecules.

Principal Investigators
Arenz, Christoph Prof. Dr. (Details) (Organic Synthesis)

Financer
DFG: Sachbeihilfe

Duration of Project
Start date: 03/2007
End date: 02/2010

Last updated on 2020-09-03 at 23:21